I’m getting into Milton Diamond PhD at the moment, I can find plenty of other PhD’s to examine but this one has particular interest for me as he claims to have a report on a person treated for CAIS and Klinefelter’s syndrome at the same time – well does he say ‘treated?’ No he doesn’t he says someone ‘can have’ both syndromes at the same time, which is nonsense. He reports on a person who has CAIS with XXY sex chromosomes and Milton Diamond PhD. assumes XXY always equals KS. He regularly mentions KS and XXY in the same paragraph, such as:
“One of the largest long-term studies of its kind, the so-called “Edinburgh study” , found that, at birth, babies who had KS generally were smaller in weight, length, and head circumference than were controls. The head circumference difference remained between the 10th and 25th percentiles and reflected an adverse effect on brain growth . A notable increase in height velocity occurred between the ages of 5 and 8 years of age because of the greater leg growth; however, the typical pubertal growth spurt did not differ from controls. A tendency to central obesity was seen in 75% of the XXY boys who were followed.”
But the report he’s supposedly quoting from does not say “…babies who had KS…” the report never mentions KS except when referring to other peoples reports.
The report is actually about the effects of having an additional X or Y chromosome, and deals with XXX females and and XYY males too.
So when he quotes accurately “A notable increase in height velocity occurred between the ages of 5 and 8 years of age because of the greater leg growth” he should also have quoted of the XXX females “As for the XXY boys height velocity increased during mid-childhood owing to greater leg growth”
The additional X can cause increased growth in both males and females in childhood, and as females can’t have Klinefelter’s syndrome that effect can’t be the result of hypogonadism. This result proves XXY boys can’t have Klinefelter’s syndrome in childhood. Probably why Milton Diamond PhD. made the change!
We can see increased height for XYY males too, quoting from the exact same report “…the velocity of growth increased from age 2 years continuing throughout childhood….”
But Milton Diamond PhD. has a particular goal in mind, to change current trends of research back to what they were previously, which assumed XXY and KS were identical, and as a result he deliberately misquotes and quotes selectively.
The report he references regarding a woman with CAIS does not mention Klinefelter’s syndrome, it mentions the 47XXY karyotype in a woman with CAIS, and with dubious editing he is attempting to make it look like females can have Klinefelter’s syndrome too, to the casual reader.
At the very start of Milton Diamond’s report “They are among the most commonly seen intersex conditions and have a prevalence of 2 or 3 cases/1000 population. These conditions present instances of undermasculinization and both syndromes can occur in the same individual .”
Whereas in fact Klinefelter’s syndrome is not intersex at all, KS is the symptoms of disease, and the original report by Klinefelter et al, detailed those symptoms, the symptoms of Seminiferous Tubule Dysgenesis in 9 adult males. This link goes to a pair of twins with Seminiferous Tubule Dysgenesis, which is dated 1958, and in brackets, as it wasn’t in the original publication (Klinefelter’s Syndrome) and there is no mention of the 47XXY karyotype as that discovery wasn’t made until 1959.
How then does Milton Diamond’s reference to the Klinefelter et al report dated 1942 have anything to do with the 47XXY karyotype, when those authors had no idea of chromosomes? This is the reference Milton Diamond PhD. gives “ Klinefelter HF, Reifenstein EC, Albright F. Syndrome characterized by gynecomastia, aspermatogenesis without a-Leydism, and increased excretion of follicle-stimulating hormone. J Clin Endocrinol 1942;2:615-27.”
Then under his heading of “Klinefelter’s syndrome” we read “The sex chromosome complement can vary from the most typical, 47, XXY, to XXXY, XYY XXYY, and other combinations, and, may occur with, or independent of, different mosaic conditions . Individuals who have an XXX karyotype are considered to have a Klinefelter’s variant by some investigators, although no Y chromosome is present. The presence of a Y chromosome usually leads to development as a male; persons who have XXX appear as females. Cases of individuals who had an XXY karyotype and a female phenotype have been reported .”
CAIS is obviously present from birth of the females with it, but Klinefelter’s syndrome can only manifest after the onset of puberty, and there is no undermasculinisation of XXY boys.
I have never seen any researcher who refers to XXX females and XYY males as variants of Klinefelter’s syndrome, except Milton Diamond PhD. and Linda Ann Watson MEd, Milton’s co-author.
XXX females do not ‘appear’ as females, they ‘ARE’ females!
XYY males are NEVER referred to as a variant of Klinefelter’s syndrome. They’re sometimes named after the woman who first discovered their karyotype, Patricia Jacobs.
Cases of XXY females have been reported and they are referred to as SRY Negative, whereas XXY males are SRY Positive. The SRY gene is said to be the one that controls male sexual development, so these XXY females are not related to our XXY male population. There is no association at all.
However, back before 1992 when his book ‘Sex Watching‘ was published Milton Diamond PhD. expressed a theory that XXY males were ‘pseudohermaphrodites,’ and he, in my opinion, wishes to manipulate the proven research to emphasise this theory, from page 126:
And on page 46 we can read of his idea that XXY is the same as Klinefelter’s syndrome, which makes him a very hard man to teach new tricks to! Oh and of course we read about his idea that a small penis is often if not always seen in men with Klinefelter’s syndrome:
Have I been lied to since 1976/77 do I really not have ‘good penile and scrotal development?’ Can the eye of the beholder tell the difference between an academic’s writing and the reality of existence?
To give Milton Diamond PhD. credit he does say that he no longer uses the word ‘pseudohermaphrodite’ to describe us XXY males, but he clearly does have a notion in mind that we’re really not ‘real males’ by referring to us all as intersex. Look at the picture of myself above, who can look at that image and think ‘intersex?’
In my previous post I refer to XXY men as being untrustworthy, whereas Milton Diamond PhD. assumes every word spoken by all who claim to be XXY as the ‘gods honest truth.’ Milton Diamond PhD. then references words apparently mentioned by XXY men, without corroboration, this is his reference  “McKinlay IW. The KS Story: You are not alone. Peebles, Scotland, in press.” and McKinlay just happens to be an XXY man.
I have a copy of the KS Story in my possession and it is available online as a PDF file, and is promoted by Milton Diamond PhD. The part of Milton Diamond’s report refers to it in the terms of “Gender Expression.”
“Infrequently discussed in medical descriptions of KS are individuals’ concerns with gender expressions and feelings. An unknown percentage of persons who have KS experience androgynous or feminine feelings that can develop at an early age . Some people who have KS consider themselves to be transgendered , others considered themselves to be intersexed , and others considered themselves to be transsexual.”
The  reference goes to an Australian newspaper article, hardly scientific! So if we frequently discuss a matter will that make it more common? How many XY males have these feelings and what is the reason for those feelings? Of course if you hold the view as Milton Diamond PhD. does that XXY males are not really male, but ‘pseudohermaphrodites’ or ‘intersex’ then it’s easy to assume this infrequently discussed in medical literature matter is much more common than may be thought.
If you’re interested in factual information as I am, you might be persuaded that these infrequently discussed topics are infrequent because they very rarely pop up! If XXY men did not really feel male after they were diagnosed, why didn’t they express such feelings before they were diagnosed, and be diagnosed because of those feelings? I’m talking about people who tend to have difficulty expressing themselves, from this work:
So taking XXY men at their word, is, as I have said many times before, “fraught with difficulty.”
Just because a well known PhD. doctor says something is no guarantee s/he knows what they’re talking about.